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The best way to discover which microdosing protocol suits you best is simply by trying them out. We recommend starting with Fadiman’s Protocol.

2. The Every Other Day Protocol:

This protocol was created by Microdosing institute.

People who microdose for medical reasons such as depression, (social) anxiety, ADHD, ADD, migraines or cluster headaches often benefit from microdosing  "every other day " using this protocol.

DAY 1 : Microdosing day


DAY 3 : Microdosing day


Continue for 1 to 2 months 


Two to four weeks rest

1. Fadiman Protocol

(also known as the Beginners Protocol)

DAY 1: Microdosing day

DAY 2: Off

DAY 3: Off

DAY 4: Microdosing day


Continue this cycle for four to eight weeks


Two to four weeks rest

3. Intuitive microdosing

Another way of microdosing is to do it entirely intuitively, with only one rule: you always leave at least one day between the days you take a microdose.


People who have followed any kind of microdosing protocol for one or two cycles often switch to a more intuitive way of microdosing.


Here's a set of recommendations to follow when starting

a microdosing regimen using one fadiman’s or stamet protocol.

Morning Routine:

Take the microdose pill first thing in the morning on an empty stomach,

This helps set a consistent routine for dosing.

Avoid Food & Coffee:

After taking the microdose,

refrain from consuming food or coffee for the first hour.

This can help maximize the absorption and effects of the microdose.

Set Intentions:

Before each dose, set positive intentions for the day.

This can help guide your mindset and focus during the experience.

Healthy Lifestyle:

Incorporate healthy habits into your routine, such as regular exercise and nutritious meals.

A healthy body and mind can enhance the benefits of microdosing.

Alcohol Moderation:

During the 4-week microdosing period, it's advisable to avoid alcohol consumption.

This can contribute to a more stable and effective experience


Maintain a journal to track your thoughts, feelings, and experiences throughout the day.

This can help you gain insights into how microdosing is affecting your overall well-being.

Structured Sleep Schedule:

Establish a consistent sleep routine.

Adequate and restful sleep is important for overall mental health and well-being, and it can complement the effects of microdosing

Embrace Change:

Recognize that microdosing can provide new perspectives and insights.

Be open to change and growth during this period

Mindfulness Practices:

Incorporate mindfulness techniques into your routine,

such as meditation or deep breathing exercises.

These practices can help you stay grounded and centered.

Stay Hydrated:

Drink plenty of water throughout the day to support your body's natural processes and maintain hydration.

Spend time reflecting on your thoughts and emotions regularly.

Microdosing can amplify introspection, so being aware of your mental state can be beneficial.

Mindful Reflection:

Remember, everyone's experience with microdosing can be different. It's important to listen to your body and mind, and make adjustments as needed. Always prioritize your safety and well-being.


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